The Center for Broad Explorations on Spectrum Technologies for Navigation, Environment, Surveillance, and Transportation (BEST NEST) leverages theoretical foundations and applications in the multi-disciplinary areas of wireless communications, network sciences, localization, data sciences, edge computing, control, sensing, and quantum computing. It aims to optimally plan and support Economics and Entrepreneurship in all Spectrum Related areas through vast collaboration with existing major companies and startups, and the creation of new startups. Moreover, by working closely with FCC and regulators, it will support the creation and growth of the newly imposed standards and policies for the proper use of existing and emerging frequency bands. It will also develop plans that support Education and Training at all levels. Finally, the center aims to extend its impacts globally and support technology and training in developing countries.